butabarbital will lessen the level or effect of doxorubicin liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.butabarbital will lower the level or outcome of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.butabarbital will reduce the extent or result of alprazolam by af